MIT 8.591J Systems Biology, Fall 2014 (English)

   Monday, December 16, 2024   

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Lecture 1: Introduction to the Class and Overview of Topics

Lecture 2: Input Function, Michaelis-Menten kinetics, and Cooperativity

Lecture 3: Autoregulation, Feedback and Bistability

Lecture 4: Synthetic Biology and Stability Analysis in the Toggle Switch

Lecture 5: Oscillatory Genetic Networks

Lecture 6: Graph Properties of Transcription Networks

Lecture 7: Feed-forward Loop Network Motif

Lecture 8: Introduction to Stochastic Gene Expression

Lecture 9: Causes and Consequences of Stochastic Gene Expression

Lecture 10: Stochastic Modeling

Lecture 11: Life at Low Reynolds Number

Lecture 12: Robustness and Bacterial Chemotaxis

Lecture 13: Robustness in Development and Pattern Formation

Lecture 14: Microbial Evolution Experiments and Optimal Gene Circuit Design

Lecture 15: Evolution in Finite Populations

Lecture 16: Clonal Interference and the Distribution of Beneficial Mutations

Lecture 17: Fitness Landscapes and Sequence Spaces

Lecture 18: Evolutionary Games

Lecture 19: Survival in Fluctuating Environments

Lecture 20: Parasites, the Evolution of Virulence and Sex

Lecture 21: Interspecies Interactions

Lecture 22: Ecosystem Stability, Critical Transitions, and Biodiversity

Lecture 23: Dynamics of Populations in Space

Lecture 24: The Neutral Theory of Ecology