MIT 5.08J Biological Chemistry II, Spring 2016 (English)

   Tuesday, December 10, 2024   

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MIT 5.08J Biological Chemistry II, Spring 2016 By Lecture Notes together!

Lecture 1: 1. Introduction to Biological Chemistry II

Lecture 2: 2. Protein Synthesis 1

Lecture 3: R1. Determining, Analyzing, and Understanding Protein Structures

Lecture 4: 3. Protein Synthesis 2

Lecture 5: 4. Protein Synthesis 3

Lecture 6: 5. Protein Synthesis 4

Lecture 7: R2. Pre-Steady State and Steady-State Kinetic Methods Applied to Translation

Lecture 8: 6. Protein Synthesis 5

Lecture 9: 7. Protein Synthesis 6

Lecture 10: 8. Protein Folding 1

Lecture 11: R3. Pre-Steady State and Steady-State Kinetic Methods Applied to Translation

Lecture 12: 9. Protein Folding 2

Lecture 13: 10. Protein Folding 3

Lecture 14: 11. Protein Folding 4

Lecture 15: R4. Purification of Native and Mutant Ribosomes, Protein Purification

Lecture 16: 12. Protein Degradation 1

Lecture 17: 13. Protein Degradation 2

Lecture 18: 14. Protein Degradation 3

Lecture 19: R5. Overview of Cross-Linking, Including Photo-Reactive Cross-Linking Methods

Lecture 20: 15. PK and NRP Synthases 1

Lecture 21: 16. PK and NRP Synthases 2

Lecture 22: R6. Macromolecular Electron Microscopy Applied to Fatty Acid Synthase

Lecture 23: 17. PK and NRP Synthases 3

Lecture 24: 18. PK and NRP Synthases 4

Lecture 25: R7. Application of Single Molecule Methods

Lecture 26: 19. Cholesterol Biosynthesis 1

Lecture 27: 20. Cholesterol Biosynthesis 2

Lecture 28: 21. Cholesterol Biosynthesis 3 & Cholesterol Homeostasis 1

Lecture 29: R8. Application of CRISPR to Study Cholesterol Regulation

Lecture 30: 22. Cholesterol Homeostasis 2

Lecture 31: 23. Cholesterol Homeostasis 3

Lecture 32: 24. Cholesterol Homeostasis 4

Lecture 33: R9. Cholesterol Homeostasis and Sensing

Lecture 34: 25. Cholesterol Homeostasis 5 & Metal Ion Homeostasis 1

Lecture 35: 26. Metal Ion Homeostasis 2

Lecture 36: 27. Metal Ion Homeostasis 3

Lecture 37: R10. Metal-Binding Studies and Dissociation Constant Determination

Lecture 38: 28. Metal Ion Homeostasis 4

Lecture 39: 29. Metal Ion Homeostasis 5

Lecture 40: R11. Mass Spectrometry

Lecture 41: 30. Metal Ion Homeostasis 6

Lecture 42: 31. Metal Ion Homeostasis 7 & Reactive Oxygen Species 1

Lecture 43: R12. Mass Spectrometry of the Cysteine Proteome

Lecture 44: 32. Reactive Oxygen Species 2

Lecture 45: 33. Reactive Oxygen Species 3

Lecture 46: 34. Reactive Oxygen Species 4 & Nucleotide Metabolism 1

Lecture 47: R13. Fluorescence Methods

Lecture 48: 35. Nucleotide Metabolism 2

Lecture 49: 36. Nucleotide Metabolism 3